| 发明名称 |
COMBINATIONS COMPRISING ANTIMUSCARINIC AGENTS AND PDE4 INHIBITORS |
| 摘要 |
Combinations comprising (a) a PDE4 Inhibitor and (b) an antagonist of M3 muscarinic receptors which is 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane, in the form of a salt having an anion X, which is a pharmaceutically acceptable anion of a mono or polyvalent acid are useful, e.g., for the treatment of respiratory disease, e.g., asthma or chronic obstructive pulmonary diseases. |
| 申请公布号 |
US2017049756(A1) |
申请公布日期 |
2017.02.23 |
| 申请号 |
US201615080475 |
申请日期 |
2016.03.24 |
| 申请人 |
Gras Escardo Jordi;Llenas Calvo Jesus;Ryder Hamish;Orviz Diaz Pio |
发明人 |
Gras Escardo Jordi;Llenas Calvo Jesus;Ryder Hamish;Orviz Diaz Pio |
| 分类号 |
A61K31/439;A61K45/06;A61K9/00;A61K47/26;A61K31/44;A61K31/277 |
主分类号 |
A61K31/439 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A combination which comprises (a) a PDE4 inhibitor and (b) an antagonist of M3 muscarinic receptors which is 3(R)-(2-hydroxy-2,2-dithien-2-ylacetoxy)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane, in the form of a salt having an anion X, which is a pharmaceutically acceptable anion of a mono or polyvalent acid. |
| 地址 |
Barcelona ES |
