SYSTEMS AND METHODS FOR EXTRACTION AND SURFACE-ENHANCED RAMAN SPECTROSCOPY DETECTION OF METAL NANOPARTICLES

摘要

Systems and methods are provided herein for the extraction, detection and measurement of MNPs in complex matrices in particular, the method includes mixing a solution including a predetermined organic substance with a matrix including the metal nanoparticles, the predetermined organic substance adapted to bind to the metal nanoparticles, to facilitate extraction by an organic solvent and to provide a distinct SERS signal, the mixing resulting in a suspension, adding a solution of a predetermined organic extraction solvent to the suspension, extracting and separating the metal nanoparticles; the metal nanoparticles, after extraction, functionalized by binding with the predetermined organic substance, and extracting and separating the metal nanoparticles; the metal nanoparticles, after extraction, functionalized by binding with the predetermined organic substance; and performing SERS imaging on the functionalized metal nanoparticles in order to detect metals nanoparticles.

主权项

1. A method for extraction and detection of metal nanoparticles from matrices, the method comprising:
mixing a solution including a predetermined organic substance with a matrix including the metal nanoparticles; the predetermined organic substance adapted to bind to the metal nanoparticles, to facilitate extraction by an organic solvent and to provide a distinct SERS signal; the mixing resulting in a suspension; adding a solution of a predetermined organic extraction solvent to the suspension; extracting and separating the metal nanoparticles, the metal nanoparticles, after extraction, functionalized by binding with the predetermined organic substance; and performing SERS imaging on the functionalized metal nanoparticles in order to detect metals nanoparticles.