| 主权项 |
1. A compound of Formula (I) or a pharmaceutically acceptable salt thereof, wherein: R1 is phenyl, 5- to 6-membered aromatic heterocycle, 8- to 10-membered bicyclic heterocycle or 11- to 14-membered tricyclic heterocycle, each of which is unsubstituted or substituted with one or more substituents independently selected from the group consisting of -halo, —C1-C4 alkyl, —C3-C8 monocyclic cycloalkyl, halo-substituted C1-C4 alkyl, —CN, —OH, —C1-C4 alkoxy, —O—C3-C8 monocyclic cycloalkyl, halo-substituted C1-C4 alkoxy and 3- to 7-membered monocyclic heterocycle; each R2 is independently hydrogen, —C1-C4 alkyl or —C3-C6 monocyclic cycloalkyl with the proviso that both R2 are not hydrogen, or both R2 together with the carbon atom they are attached to form a C3-C6 monocyclic cycloalkyl, wherein each —C1-C4 alkyl and —C3-C6 monocyclic cycloalkyl is unsubstituted or substituted with one or more substituents independently selected from the group consisting of -halo, —OH, —C1-C4 alkoxy, —O—C3-C8 monocyclic cycloalkyl which is unsubstituted or substituted with halo, halo-substituted C1-C4 alkyl or halo-substituted C1-C4 alkoxy; Y is pyridinyl or phenyl, each of which is unsubstituted or substituted with one or more substituents independently selected from the group consisting of -halo, —C1-C4 alkoxy, halo-substituted C1-C4 alkoxy, —C1-C4 alkyl, halo-substituted C1-C4 alkyl, —CN and —OH; and Z is nitrogen-containing 3- to 7-membered monocyclic heterocycle which is unsubstituted or substituted with one or more substituents independently selected from the group consisting of -halo, —C1-C4 alkyl, halo-substituted C1-C4 alkyl, —C1-C4 alkoxy and —OCF3. |
