发明名称 RESONANCE RAMAN SPECTROSCOPY ANALYZER INSTRUMENT FOR BIOMOLECULES IN TISSUES AND CELLS
摘要 A method to detect vibrations associated with biomolecules in tissues and cellsuses Resonance Raman (RR) spectroscopy to measure specific biomolecules in tissue and cells signals. The changes of RR lines of key molecules present to the chemical conformations and change due to disease such as cancer and heart disease. Biomolecules are collagen, flavins, tryptophan, NADH, NAD, etc. The laser beams excite RR of vibration associated with absorption of the key native molecules in tissue (Tryptophan, NADH, Flavins, Collagen, carotenoids, porphyrins and others. The margin assessment and RR images in 2D and 3D regions are found by RR signals using position scanners. The intensity and the numbers of molecule fingerprints indicate the prescence of and the degree of the changes of chemical conformations.
申请公布号 US2017049327(A1) 申请公布日期 2017.02.23
申请号 US201615243391 申请日期 2016.08.22
申请人 Alfano Robert R. 发明人 ALFANO ROBERT;Liu Cheng-hui
分类号 A61B5/00;A61B1/00;A61B10/00;A61B1/05;A61B5/08;A61B5/20;A61B1/07;A61B1/06 主分类号 A61B5/00
代理机构 代理人
主权项 1. A method of detecting clinical in vivo lesions comprises the steps of using resonant Raman (RR) to detect in vivo cancer by measuring RR of molecule fingerprint modes to determine the prescence of lesion sites in human tissue, and using ratios of intensities at two or more frequencies of cancer and tissues vibrational modes
地址 Bronx NY US