发明名称 |
Method for the preparation of triglycerides of medium-chain length fatty acids |
摘要 |
A method is disclosed for the preparation of glycerol esters (triglycerides) of medium-chain length monocarboxylic fatty acids which consists of the reaction of the precursor free fatty acid and glycerol in the presence of a catalyst under partial vacuum. The process preferably uses a metal catalyst such as an oxide or a chloride of tungsten, molybdenum, calcium, zinc, chromium or magnesium. The method of the invention allows the preparation in high yield and high purity (>99.5%) of the final triglyceride. The present method allows the formation of triglycerides without solvent. Are also contemplated, the triglyceride obtained by the method, and the pharmaceutical composition containing the triglyceride as an excipient or as an active ingredient. |
申请公布号 |
AU2013225572(B2) |
申请公布日期 |
2017.02.23 |
申请号 |
AU20130225572 |
申请日期 |
2013.02.28 |
申请人 |
ProMetic Pharma SMT Limited |
发明人 |
Boulos, Zacharie;Duceppe, Jean-Simon;Penney, Christopher |
分类号 |
C07C67/08;A61K47/14;C07C69/30;C11C3/06 |
主分类号 |
C07C67/08 |
代理机构 |
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代理人 |
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