Substance delivery devices, systems and methods

摘要

A substance delivery device includes an elongated tubular body having opposing proximal and distal ends, and a diaphragm that is in slideable sealing engagement with an inside wall of the tubular body. The diaphragm is movable in opposite first and second directions within the tubular body. A substance is contained within the tubular body between the diaphragm and the tubular body distal end, and a slave fluid is contained within the tubular body between the diaphragm and the tubular body proximal end. When pressure is exerted on the slave fluid, the slave fluid causes the diaphragm to move and eject the substance through the tubular body distal end.

主权项

1. A system for delivering a substance to a patient, the system comprising:
a trajectory guide configured to be secured to a body of the patient; a cannula supported by the trajectory guide, the cannula comprising a cannula body defining at least one longitudinally extending lumen, an inlet port, and at least one exit port, wherein the trajectory guide provides X-Y adjustment and pitch and roll adjustment for the cannula; a substance delivery device, comprising:
an elongated tubular body comprising opposing proximal and distal ends, each of the proximal and distal ends comprising a respective connector;a diaphragm that is in slideable sealing engagement with an inside wall of the tubular body, wherein the diaphragm is movable in opposite first and second directions within the tubular body; anda slave fluid contained within the tubular body between the diaphragm and the tubular body proximal end; and a syringe in fluid communication with the tubular body proximal end via first flexible tubing having a connector that is matingly and removably secured to the tubular body proximal end connector, wherein the syringe and the first flexible tubing contain the slave fluid, wherein activation of the syringe to cause the slave fluid to move the diaphragm in the second direction causes a substance to be loaded within the tubular body between the diaphragm and the tubular body distal end; wherein the at least one longitudinally extending lumen of the cannula is fluidly connected to the tubular body distal end via second flexible tubing, and wherein the cannula is adapted to transfer the substance from the tubular body to a selected location in the patient via the at least one exit port upon activation of the syringe to cause the slave fluid to move the diaphragm in the first direction.