发明名称 Hidtil ukendte peptider til behandling og forebyggelse af immunrelaterede sygdomme, herunder behandling og forebyggelse af infektion ved modulering af naturlig immunitet
摘要 In one aspect, the present invention provides isolated novel peptides that can be used to modulate innate immunity in a subject. and/or for the treatment of an immune-related disorder, including treating and preventing infection by modulating innate immunity. Also provided are an agent reactive with the peptide, a pharmaceutical composition that includes the peptide, an isolated nucleic acid molecule encoding the peptide, a recombinant nucleic acid construct that includes the nucleic acid molecule, at least one host cell comprising the recombinant nucleic acid construct, and a method of producing the peptide using the host cell. The present invention further provides a method for treating and/or preventing infection in a subject by administering the peptide of the invention to the subject, thereby modulating innate immunity in the subject. Additionally, the present invention provides a method for predicting whether a subject would be responsive to treatment with a peptide of the invention.
申请公布号 DK2236608(T3) 申请公布日期 2017.02.20
申请号 DK20100003191T 申请日期 2006.10.04
申请人 Soligenix, Inc. 发明人 DONINI, Oreola;ROZEK, Annett;LENTZ, Shannon, Wayne
分类号 A61K38/00;C07K5/08;C07K5/103;C07K5/11;C07K7/00;C07K7/06;C07K7/08;C12N15/11;C12Q1/37;G01N33/569 主分类号 A61K38/00
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