| 发明名称 |
COMPOSITIONS AND METHODS FOR CANCER EXPRESSING PDE3A OR SLFN12 |
| 摘要 |
The present invention features improved methods of identifying patients having cancer (e.g., melanoma, adenocarcinoma, lung, cervical, liver or breast cancer) using biomarkers (e.g., PDE3A, SLFN12) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention (e.g., DNMDP, zardaverine, and anagrelide). |
| 申请公布号 |
WO2017027854(A1) |
申请公布日期 |
2017.02.16 |
| 申请号 |
WO2016US46912 |
申请日期 |
2016.08.12 |
| 申请人 |
THE BROAD INSTITUTE, INC.;DANA-FARBER CANCER INSTITUTE, INC.;BAYER PHARMA AG |
发明人 |
DE WAAL, Luc;MEYERSON, Matthew;GREULICH, Heidi;SCHENONE, Monica;BURGIN, Alex;SACK, Ulricke |
| 分类号 |
A61K8/40;A61K31/00;A61K31/01;A61K31/04;A61K31/05;A61K31/13;A61K31/195;A61K31/50;G01N33/574 |
主分类号 |
A61K8/40 |
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