New process for the synthesis of (2E)-3-(3,4-dimethoxyphenyl)prop-2-enenitrile, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid

摘要

New Process for the Synthesis of (2E)-3-(3,4 Dimethoxyphenyl)prop-2-enenitrile, and Application in the Synthesis of Ivabradine and Addition Salts Thereof With a Pharmaceutically Acceptable Acid Abstract A process for the synthesis of the compound of formula (I) is disclosed: MeO (I) MeO Also disclosed is the application of the compound of formula (I) in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.