| 发明名称 |
ANIMAL MODELS FOR CANCER AND USES THEREOF |
| 摘要 |
Non-human animal cancer models are provided herein for identifying and characterizing agents useful for therapy and prophylaxis of cancers, including agents useful for diminishing side effects related to cancer therapies and reducing metastatic disease. |
| 申请公布号 |
US2017042129(A1) |
申请公布日期 |
2017.02.16 |
| 申请号 |
US201615080991 |
申请日期 |
2016.03.25 |
| 申请人 |
Buck Institute for Research on Aging ;Mayo Foundation for Medical Education and Research |
发明人 |
Campisi Judith;van Deursen Jan M.A.;Kirkland James L.;Tchkonia Tamar;Baker Darren J.;Demaria Marco |
| 分类号 |
A01K67/027;C12N15/85;A61K49/00 |
主分类号 |
A01K67/027 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A non-human animal model for cancer comprising a non-human animal that (a) exhibits a tumor and (b) comprises a transgene selectively expressed by senescent cells. |
| 地址 |
Novato CA US |
