METHODS OF SELECTING ANTIBODIES AND ANTIBODY FRAGMENTS

摘要

A multi-step method is disclosed for efficient selection of antibody or antibody fragments. In addition to the dramatically increased efficiency of finding antibodies against a given immunogen by the invented processes, the novel technology also differs from all previously known technologies in that the antibody or antibody fragments represent the most abundant antibodies induced by the immunogen, therefore having the highest potential of specificity and affinity. Utility of the invention can be found in virtually all areas that involve antibody or T cell receptor selection using any animal, against any immunogen.

主权项

1. A method for generating pharmaceutical batches of immunogen-specific antibodies or antibody fragments comprising identifying and obtaining sequences of antibody variable region from genomic DNA or complementary DNA.