| 发明名称 |
POLYNUCLEOTIDE AGENTS TARGETING HYDROXYACID OXIDASE (GLYCOLATE OXIDASE, HAO1) AND METHODS OF USE THEREOF |
| 摘要 |
The invention relates to polynucleotide agents targeting an hydroxyacid oxidase (HAOl) gene, and methods of using such polynucleotide agents to inhibit expression of HAOl and to treat subjects having an HAOl -associated disease, e.g., hyperoxaluria. |
| 申请公布号 |
WO2016205323(A8) |
申请公布日期 |
2017.02.16 |
| 申请号 |
WO2016US37563 |
申请日期 |
2016.06.15 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
HINKLE, Gregory |
| 分类号 |
C12N15/113;A61K31/7115;A61K31/712;A61K31/7125 |
主分类号 |
C12N15/113 |
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