| 发明名称 |
NASAL DRUG PRODUCTS AND METHODS OF THEIR USE |
| 摘要 |
Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided. |
| 申请公布号 |
US2017043107(A1) |
申请公布日期 |
2017.02.16 |
| 申请号 |
US201615335145 |
申请日期 |
2016.10.26 |
| 申请人 |
Opiant Pharmaceuticals, Inc. |
发明人 |
CRYSTAL Roger;WEISS Michael Brenner |
| 分类号 |
A61M11/00;A61K9/08;A61K47/18;A61K9/00;A61K31/485;A61K47/02 |
主分类号 |
A61M11/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical formulation for intranasal administration comprising, in an aqueous solution of not more than about 140 μL:
about 4 mg naloxone hydrochloride; about 0.74 mg NaCl; about 0.01 mg benzalkonium chloride; about 0.2 mg disodium edetate; and an amount of hydrochloric acid sufficient to achieve a pH of 3.5-5.5. |
| 地址 |
Santa Monica CA US |
