发明名称 酸性劣化からの微生物細胞の保護
摘要 A simple cellulose sulphate based microencapsulation technology has been applied to encapsulate bacterial or other microbial cells, which produce and release digestive enzymes and thereby provides an acid resistant shelter for these microbial cells. Surprisingly, the resulting spheres were found to provide sufficient protection for encapsulated cells from treatment with aqueous acidic solutions. Thereby the cellulose sulphate microencapsulated cells, such as probiotics are now enabled to survive passage, for example, through the stomach after consumption by a human or animal with a higher survival rate than those not within a microcapsule. After passing the stomach these cells are delivering products produced by them, e.g. enzymes or other nutrition factors. This technology therefore proves to be very useful in providing digestive or otherwise beneficial enzymes and/or of living microbial cells, into the lower gastrointestinal tract, where they could confer their health benefit to the host.
申请公布号 JP6081374(B2) 申请公布日期 2017.02.15
申请号 JP20130550866 申请日期 2012.01.25
申请人 オーストリアノヴァ シンガポール プライベート リミテッド 发明人 グエンツバーグ、ウォルタ エイチ.;ブラントナ、エヴァ マリア;サルモンズ、ブライアン サルモンズ;ダンガーフィールド、ジョン エィ.
分类号 A61K35/66;A61K9/50;A61K47/32;A61K47/38;A61P1/04;A61P1/12;A61P3/04;A61P19/02;C12N1/00 主分类号 A61K35/66
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