| 发明名称 | Vaccine delivery method | ||
| 摘要 | The present invention includes a composition including as one component a slurry matrix that is a liquid at room temperature and a gel at physiological pH, physiological salt concentrations and/or physiological temperatures and as a second component one or more antigens. Also include are methods of inducing an immune response in a subject and vaccinating a subject by administering such compositions. | ||
| 申请公布号 | US9566338(B2) | 申请公布日期 | 2017.02.14 |
| 申请号 | US201313793329 | 申请日期 | 2013.03.11 |
| 申请人 | University of Georgia Research Foundation, Inc. | 发明人 | Harn Donald A.;Queiroz Rafaella;McEwen Lisa |
| 分类号 | A61K38/02;A61K35/62;A61K39/39;C07K14/435;A61K47/42;A61K39/00;A61K39/02;A61K39/145;A61K39/29;A61K39/104;A61K39/12;A61K9/00;A61K9/06 | 主分类号 | A61K38/02 |
| 代理机构 | Mueting, Raasch & Gebhardt, P.A. | 代理人 | Mueting, Raasch & Gebhardt, P.A. |
| 主权项 | 1. A composition comprising as one component a peptide hydrogel that is a liquid at room temperature and a gel at physiological pH, physiological salt concentrations and/or physiological temperatures and as another component one or more vaccine antigens, wherein the vaccine antigen comprises a schistosomiasis antigen, and wherein the schistosome antigen comprises a SjCTPI polypeptide, a SjCTPI-Hsp70 polypeptide, a SjC23 polypeptide, and/or a SjC23-Hsp70 polypeptide, or an antigenic fragment thereof. | ||
| 地址 | Athens GA US | ||