Vaccine immunotherapy

摘要

A composition for treating cancer, including synergistic amounts of a primary cell-derived biologic having the cytokines IL-1, IL-2, IL-6, IL-8, TNF-α, and IFN-γ, and a cancer vaccine having at least one antigen. A composition comprising synergistic amounts of the primary cell-derived biologic in combination with at least one adjuvant. A method of treating cancer by administering the composition. A method of reversing immune suppression and gaining immunity to cancer. A method of producing an immune response to an exogenous antigen. A method of enhancing an immune response in a patient by administering the primary cell-derived biologic in combination with at least one adjuvant, and enhancing the immune response of the patient by a synergistic interaction of the primary cell-derived biologic and the adjuvant. A method of increasing function of an immune system.

主权项

1. A composition for use in eliciting an immune response in a patient, the composition comprising:
(a) a primary cell-derived biologic including IL-1, IL-2, IL-6, IL-8, TNF-α, and IFN-γ, and (b) a vaccine comprising a viral vector encoding at least one antigen, wherein the viral vector is a retrovirus, adenovirus, adeno-associated virus (AAV), herpes virus, or poxvirus.