ANTIBODY-DRUG CONJUGATES FOR TARGETING CD56-POSITIVE TUMORS
摘要
The identification and characterization of two fully human CD56-specific monoclonal antibodies targeting spatially separated epitopes proximal and distal to the plasma membrane is described. Also described are antibody-drug conjugates (ADCs) of the identified antibodies and their use for targeting CD56-expressing tumor cells.
申请公布号
WO2017023780(A1)
申请公布日期
2017.02.09
申请号
WO2016US44777
申请日期
2016.07.29
申请人
THE UNITED STATES OF AMERICA, as represented by the secretary, DEPARTMENT OF HEALTH AND HUMAN SERVICES;THE CHILDREN'S HOSPITAL OF PHILADELPHIA
