| 发明名称 |
PREPARATION CONTAINING TETRACYCLIC COMPOUND AT HIGH DOSE |
| 摘要 |
An improved solubility of a pharmaceutical composition or formulation containing a large amount of 9-ethyl-6,6-dimethyl-8-(4-morpholin-4-yl-piperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile or a salt thereof can be achieved by forming granules of the compound or salt thereof and allowing the granules to be present together with a disintegrating agent. |
| 申请公布号 |
US2017035773(A1) |
申请公布日期 |
2017.02.09 |
| 申请号 |
US201515304133 |
申请日期 |
2015.04.24 |
| 申请人 |
Chugai Seiyaku Kabushiki Kaisha |
发明人 |
Tomimatsu Takashi;OKAZAKI Kensuke;OGAWA Yumi;YAMAMURA Takahiro |
| 分类号 |
A61K31/5377;A61K9/16 |
主分类号 |
A61K31/5377 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pharmaceutical composition comprising (i) a granule containing a compound represented by formula (I) or a salt thereof and (ii) a disintegrating agent. |
| 地址 |
Kita-ku, Tokyo JP |
