发明名称 |
METHOD OF CHROMATOGRAPHIC SEPARATION |
摘要 |
A means of isolating specific stereoisomers and enantiomers from a complex mixture containing a possibility of 32 different stereoconfigurations, thus concentrating the stereoisomer or enantiomer to a high degree of purity. |
申请公布号 |
US2017036994(A1) |
申请公布日期 |
2017.02.09 |
申请号 |
US201615331329 |
申请日期 |
2016.10.21 |
申请人 |
The Procter & Gamble Company |
发明人 |
HOKE Steven Hamilton;LEI Qingxin;MOTLAGH Safa;HAUGHT John Christian;REILLY Michael;SREEKRISHNA Koti Tatachar;LIN Yakang |
分类号 |
C07C231/24 |
主分类号 |
C07C231/24 |
代理机构 |
|
代理人 |
|
主权项 |
1. A method of separating specific stereoisomers using supercritical fluid chromatography comprising:
a. providing a column with Amylose tris [(S)-α-methylbenzylcarbamate] (AS-H); b. providing a column with Amylose tris (3,5-dimethylphenylcarbamate) (AD-H); c. providing compound 28; wherein compound 28 is run through the AS-H column and then run through the AD-H column to separate stereoisomers. |
地址 |
Cincinnati OH US |