发明名称 |
METHODS TO INDUCE TARGETED PROTEIN DEGRADATION THROUGH BIFUNCTIONAL MOLECULES |
摘要 |
The present application provides bifunctional compounds which act as protein degradation inducing moieties. The present application also relates to nucleic acids, polypeptides, cells, and methods for highly regulated, targeted degradation of proteins through the use of the bifunctional compounds. |
申请公布号 |
WO2017024317(A2) |
申请公布日期 |
2017.02.09 |
申请号 |
WO2016US46087 |
申请日期 |
2016.08.08 |
申请人 |
DANA-FARBER CANCER INSTITUTE, INC. |
发明人 |
BRADNER, James;BUCKLEY, Dennis;WINTER, Georg |
分类号 |
A61K35/17 |
主分类号 |
A61K35/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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