发明名称 |
NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME |
摘要 |
The present invention relates to novel compounds having histone deacetylase 6 (HDAC6) inhibitory activity, isomers thereof, or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions comprising the same, a method of treating disease using the composition, and methods for preparing the novel compounds. The novel compounds according to the present invention have histone deacetylase 6 (HDAC6) inhibitory activity, and are effective for the prevention or treatment of HDAC6-associated diseases, including cancer, inflammatory diseases, autoimmune diseases, neurological diseases and neurodegenerative disorders. |
申请公布号 |
EP3116859(A4) |
申请公布日期 |
2017.02.08 |
申请号 |
EP20150762410 |
申请日期 |
2015.03.12 |
申请人 |
Chong Kun Dang Pharmaceutical Corp. |
发明人 |
SONG, Hyeseung;LEE, Changgon;KWAK, Dalyong;LEE, Jaeyoung;BAE, Suyeal;KIM, Yuntae;BAE, Daekwon;HA, Nina;BAE, Miseon;KIM, Jihyun |
分类号 |
C07D241/12;A61K31/496;A61P29/00;C07D241/04 |
主分类号 |
C07D241/12 |
代理机构 |
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代理人 |
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地址 |
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