发明名称 Trk-INHIBITING COMPOUND
摘要 The present invention provides a drug containing a compound having Trk-inhibiting activity as an active ingredient in prophylaxis and/or therapy for Trk-related diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease. A compound represented by the general formula (I), wherein all symbols represent the same meanings as described in the specification, a salt thereof, an N-oxide thereof, a solvate thereof or a prodrug thereof is useful as a drug component having Trk-inhibiting activity in prophylaxis and/or therapy of diseases such as pain, pruritus, lower urinary tract dysfunction, asthma, allergic rhinitis, inflammatory bowel disease or Chagas disease.;
申请公布号 US2017027939(A1) 申请公布日期 2017.02.02
申请号 US201615291700 申请日期 2016.10.12
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 TAKEUCHI Jun;ITADANI Satoshi;HASHIMURA Kazuya;IKURA Masahiro;HIGASHINO Masato;YASUHIRO Tetsuya;NAGAURA Takeshi
分类号 A61K31/506 主分类号 A61K31/506
代理机构 代理人
主权项 1. A method for prophylaxis and/or treatment of pain comprising, administering to a patient an effective amount of 1-(2-(4-(2-amino-5-fluoropyridin-3-yl)phenoxy)pyrimidin-5-yl)-3-(2-(pyridin-3-yl)-5-(trifluoromethyl)phenyl)urea or a salt thereof.
地址 Osaka JP