| 发明名称 |
POLYPEPTIDE AND ANTI-TUMOR AGENT |
| 摘要 |
Provided is a polypeptide comprising an R domain of CRM197 and comprising one or more amino acid substitutions or deletions at positions selected from the group consisting of 391, 460, 466, 467, 468, 472, 507, and 520 of the R domain. |
| 申请公布号 |
US2017029474(A1) |
申请公布日期 |
2017.02.02 |
| 申请号 |
US201415112756 |
申请日期 |
2014.10.08 |
| 申请人 |
OSAKA UNIVERSITY |
发明人 |
MEKADA Eisuke |
| 分类号 |
C07K14/34;A61K38/16;A61K45/06 |
主分类号 |
C07K14/34 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A polypeptide comprising an R domain of CRM197, the R domain comprising at least one amino acid substitution selected from the group consisting of H391K, R460H, V468T, R472K, D507N, and H520K. |
| 地址 |
Osaka JP |
