发明名称 |
FUSION PROTEINS OF HUMAN PROTEIN FRAGMENTS TO CREATE ORDERLY MULTIMERIZED IMMUNOGLOBULIN FC COMPOSITIONS WITH ENHANCED COMPLEMENT BINDING |
摘要 |
The current invention involves a series of fully recombinant multimerized forms of immunoglobulin Fc which thereby present polyvalent immunoglobulin Fc to immune cell receptors. The fusion proteins exist as both homodimeric and highly ordered multimeric fractions, termed stradomers. The invention involves stradomers that increase multimerization and bind preferentially to complement and that are useful in the treatment and prevention of disease. |
申请公布号 |
WO2017019565(A2) |
申请公布日期 |
2017.02.02 |
申请号 |
WO2016US43746 |
申请日期 |
2016.07.22 |
申请人 |
GLIKNIK INC. |
发明人 |
BLOCK, David S.;OLSEN, Henrik |
分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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