发明名称 |
PROBE REAGENT AND FISH USING PROBE REAGENT |
摘要 |
Provided are: a probe reagent which is capable of stably yielding a fluorescence signal in FISH while inhibiting non-specific adsorption by the use of a nucleic acid molecule having a smaller number of bases than a BAC probe; and FISH using the probe reagent. The probe reagent is for in situ hybridization and comprises: phosphor-integrated nanoparticles containing phosphors integrated therein; and a nucleic acid molecule having a prescribed nucleic acid sequence, which phosphor-integrated nanoparticles and nucleic acid molecule are bound with each other. |
申请公布号 |
US2017029878(A1) |
申请公布日期 |
2017.02.02 |
申请号 |
US201515125651 |
申请日期 |
2015.03.20 |
申请人 |
KONICA MINOLTA, INC. |
发明人 |
ISODA Takeshi;SEKIGUCHI Mitsuru;HATANAKA Yutaka;KURIHARA Yoshikazu |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
1. A probe reagent for in situ hybridization, comprising:
phosphor-integrated nanoparticles containing phosphors integrated therein; and a nucleic acid molecule having a prescribed nucleic acid sequence, said phosphor-integrated nanoparticles and said nucleic acid molecule being bound with each other. |
地址 |
Tokyo JP |