发明名称 PROBE REAGENT AND FISH USING PROBE REAGENT
摘要 Provided are: a probe reagent which is capable of stably yielding a fluorescence signal in FISH while inhibiting non-specific adsorption by the use of a nucleic acid molecule having a smaller number of bases than a BAC probe; and FISH using the probe reagent. The probe reagent is for in situ hybridization and comprises: phosphor-integrated nanoparticles containing phosphors integrated therein; and a nucleic acid molecule having a prescribed nucleic acid sequence, which phosphor-integrated nanoparticles and nucleic acid molecule are bound with each other.
申请公布号 US2017029878(A1) 申请公布日期 2017.02.02
申请号 US201515125651 申请日期 2015.03.20
申请人 KONICA MINOLTA, INC. 发明人 ISODA Takeshi;SEKIGUCHI Mitsuru;HATANAKA Yutaka;KURIHARA Yoshikazu
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
主权项 1. A probe reagent for in situ hybridization, comprising: phosphor-integrated nanoparticles containing phosphors integrated therein; and a nucleic acid molecule having a prescribed nucleic acid sequence, said phosphor-integrated nanoparticles and said nucleic acid molecule being bound with each other.
地址 Tokyo JP