METHODS FOR TREATING VIRAL DISORDERS

摘要

Disclosed are methods of treating viral disorders via the administration of an inducing agent and an anti-viral agent. In one embodiment, the inducing agent and the anti-viral agent are administered for about five days, and the anti-viral agent is subsequently administered without the inducing agent for an additional period of about sixteen days for a total cycle of about 21 days.

主权项

1. A method for treating neoplasma associated with Epstein-Barr infection in a subject, comprising
administering to the subject an inducing agent to induce expression of a viral gene product in a virus-infected cell of the subject and an anti-viral agent whose anti-viral activity is directed to the viral gene product expressed, wherein said inducing agent is a HDAC inhibitor, wherein the HDAC inhibitor is a hydroxamic acid derivative, and wherein said subject is not treated with radiation therapy.