METHOD FOR DIAGNOSING AND TREATING MULTIPLE MYELOMA.

摘要

The invention is in the field of medical treatments and relates to the treatment of cancer, in particular multiple myeloma (MM). Even more in particular it provides means and methods for the improved treatment of certain subgroups of MM patients, more in particular subjects with a poor prognosis. In a particular embodiment, the invention provides a method of treatment wherein subjects with a poor prognosis are selected and treated with a proteasome inhibitor such as Bortezomib. The invention further provides means and methods for identifying subjects with a poor prognosis. More in particular, the invention provides a composition comprising a proteasome inhibitor for use in the treatment of a subject with multiple myeloma wherein the subject has been diagnosed with an amp1q chromosomal aberration.