| 发明名称 | (2S, 5R)-sulfuric acid mono-{[(4-aminopiperidin-4-yl) carbonyl]-7-oxo-1,6-diaza-bicyclo[3.2.1]-oct-6-yl} ester | ||
| 摘要 | A process for preparation of (2S, 5R)-Sulfuric acid mono-{[(4-aminopiperidin-4-yl) carbonyl]-7-oxo-1,6-diaza-bicyclo[3.2.1]-oct-6-yl} ester is disclosed which comprises reacting a compound of Formula (II) with a compound of Formula (III) to obtain a compound of Formula (IV).; | ||
| 申请公布号 | US9556174(B2) | 申请公布日期 | 2017.01.31 |
| 申请号 | US201314769805 | 申请日期 | 2013.10.12 |
| 申请人 | WOCKHARDT LIMITED | 发明人 | Wankhede Karuna Suresh;Surwase Mahesh Manikrao;Bhawsar Satish;Deshpande Prasad Keshav;Yeole Ravindra Dattatraya;Patel Mahesh Vithalbhai |
| 分类号 | C07D471/08 | 主分类号 | C07D471/08 |
| 代理机构 | Bio Intelectual Property Services LLC (Bio IPS) | 代理人 | Bio Intelectual Property Services LLC (Bio IPS) ;Zaghmout O. (Sam) |
| 主权项 | 1. A process for preparation of a compound of Formula (I), comprising: reacting a compound of Formula (II) with a compound of Formula (III) in presence of a solvent to obtain a compound of Formula (IV) wherein Boc is a tert-butyloxycarbonyl and wherein OBn is a benzyloxy; (b) hydrogenolysis of a compound of Formula (IV) to obtain a compound of Formula (V); (c) sulfonating a compound of Formula (V) to obtain a compound of Formula (VI); and (d) reacting a compound of Formula (VI) with trifluoracetic acid to obtain a compound of Formula (I). | ||
| 地址 | Bandra East, Mumbai IN | ||