发明名称 |
SYSTEMS AND METHODS FOR TREAMENTS OF AN EYE WITH A PHOTOSENSITIZER |
摘要 |
A formulation for an eye treatment includes a photosensitizer and a permeability enhancing composition. The permeability enhancing composition includes one or more permeability enhancers. The permeability enhancing composition has a hydrophilic and lipophilic balance increases a permeability of an area of the eye for the photosensitizer. The hydrophilic and lipophilic balance can be characterized by a Hydrophile-Lipophile Balance (HLB) number. For example, the area of the eye may include a corneal epithelium, the photosensitizer may include riboflavin, and the permeability enhancing composition may have a corresponding HLB number between approximately 12.6 and approximately 14.6. |
申请公布号 |
WO2017015471(A1) |
申请公布日期 |
2017.01.26 |
申请号 |
WO2016US43359 |
申请日期 |
2016.07.21 |
申请人 |
AVEDRO, INC. |
发明人 |
KAMAEV, Pavel;FRIEDMAN, Marc |
分类号 |
A61K31/525;A61K47/34;A61N5/06;A61P27/02;A61P31/04;A61P33/02 |
主分类号 |
A61K31/525 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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