The invention relates generally to compounds that modulate the activity of TGFβR-1 and TGFβ R-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.
申请公布号
WO2017015425(A1)
申请公布日期
2017.01.26
申请号
WO2016US43252
申请日期
2016.07.21
申请人
BRISTOL-MYERS SQUIBB COMPANY
发明人
HARIKRISHNAN, Lalgudi S.;FINK, Brian E.;BORZILLERI, Robert M.;TONUKUNURU, Gopikishan;RAHAMAN, Hasibur;WARRIER, Jayakumar Sankara;SESHADRI, Balaji