| 摘要 |
The present invention provides a wound dressing and method for treating wounds that introduces and/or promotes the growth of non-pathogenic bacteria or single-celled eukaryotes such as fungi, yeast, or algae over pathogenic bacteria or saprophytic fungi within a would or on the skin. It is intended that the non-pathogenic species will compete with the pathogenic organisms and reduce their relative proportion of the total bioburden population. A single microbial or algal species or a mixture of organisms can be delivered at one time, or in sequence. Organisms can be in the planktonic form in a liquid suspension that is sprayed or poured onto the wound, or immobilized as spores on a solid or semi-solid substrate that is applied to the wound (e.g., in a wound dressing). In addition dressings that modulate the skin or wound environment to select one or one group of organisms over another are described. |
