发明名称 AMPLIFICATION CONTROL FOR COMPLEX NUCLEIC ACIDS
摘要 What is described is a method for quantitative and qualitative analysis of complex template nucleic acids to be analyzed. The method comprises the co-amplification of a control nucleic acid with the complex template nucleic acid by means of isothermal strand displacement reaction. The method of the invention further comprises the determination of the amount of amplified control nucleic acid as measure for the determination of the quantity and/or quality of the complex template nucleic acid used. The present invention also relates to a kit for carrying out a method of the invention. Furthermore, the use of the method of the invention or the kit of the invention for standardisation of whole-genome, whole-transcriptome and whole-bisulfitome analyses is described.
申请公布号 EP2438192(B1) 申请公布日期 2017.01.25
申请号 EP20100726931 申请日期 2010.06.03
申请人 Qiagen GmbH 发明人 KORFHAGE, Christian;FISCH, Evelyn
分类号 C12Q1/68 主分类号 C12Q1/68
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