| 发明名称 |
DOSING OF CABOZANTINIB FORMULATIONS |
| 摘要 |
The invention relates to administration of various pharmaceutical formulations of N- (4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1- dicarboxamide, (cabozantinib) a c-Met inhibitor, and its metabolites, to achieve desirable pharmacokinetic and pharmacodynamic effects. |
| 申请公布号 |
EP3119476(A1) |
申请公布日期 |
2017.01.25 |
| 申请号 |
EP20150714340 |
申请日期 |
2015.03.17 |
| 申请人 |
Exelixis, Inc. |
发明人 |
AFTAB, Dana, T.;NAGANATHAN, Sriram;XU, Wei;LACY, Steven |
| 分类号 |
A61P35/00;A61K9/00;A61K9/20;A61K9/48;A61K31/47;C07C233/60;C07C305/24;C07D215/22 |
主分类号 |
A61P35/00 |
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