发明名称 |
HETEROARYL SYK INHIBITORS |
摘要 |
The invention relates to new substituted heteroaryls of formula (1), wherein A is selected from the group consisting of N and CH, D is CH, E is selected from the group consisting of C and N, T is C, G is selected from the group consisting of C and N, and wherein each of the broken (dotted) double bonds in ring 1 are selected from either a single bond or a double bond under the proviso that all single and double bonds of ring 1 are arranged in such a way that they all form together with ring 2 an aromatic ring system, and wherein R1, M and R3 are defined according to claim 1, and to the above compounds for the treatment of a disease selected from the group consisting of asthma, COPD, allergic rhinitis, allergic dermatitis, lupus erythematodes, lupus nephritis and rheumatoid arthritis. |
申请公布号 |
EP3119765(A1) |
申请公布日期 |
2017.01.25 |
申请号 |
EP20150711452 |
申请日期 |
2015.03.12 |
申请人 |
Boehringer Ingelheim International GmbH |
发明人 |
DAHMANN, Georg;HOFFMANN, Matthias;KLICIC, Jasna;LAMB, David James;MCCARTHY, Clive;NAPIER, Spencer;PARRISH, Karen;SCOTT, John;FITZGERALD, Jennifer L. Swantek;WALKER, Edward |
分类号 |
C07D403/14;A61K31/505;A61P11/06;C07D471/04;C07D487/04 |
主分类号 |
C07D403/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|