Method for treating psoriasis

摘要

The present invention provides pharmaceutical composition for treating an autoimmune disease comprising a pharmaceutically acceptable carrier and an agent capable of activating CD4+CD25+ regulatory T cells, wherein the composition is to be administered to a subject at most every 3 days.

主权项

1. A method for treating an autoimmune disease comprising administering to a subject a pharmaceutical composition comprising a pharmaceutically acceptable carrier and an agent capable of activating CD4+CD25+ regulatory T cells, wherein the agent is a humanized anti-CD4 antibody comprising an IgG1 constant domain, an H chain V domain comprising the CDRs of SEQ ID NO: 7 and an L chain V domain comprising the CDRs of SEQ ID NO: 8;
wherein said administering occurs from every week to every 31 days at a dose of the humanized anti-CD4 antibody of from 10 to 200 mg; and wherein the autoimmune disease is psoriasis.