ALLOGENEIC BONE AND/OR CARTILAGE BONE MEAL AND PREPARATION METHOD AND USE THEREOF

摘要

Disclosed are an allogeneic bone and/or cartilage bone meal and a preparation method and use thereof, comprising the following steps: (1) pulverizing an allogeneic bone and/or cartilage; (2) blending the pulverized allogeneic bone and/or cartilage and a nuclease to conduct an enzymatic reaction; (3) incubating and washing the pulverized allogeneic bone and/or cartilage with a detergent and an optional first chelating agent; (4) optionally conducting a decalcification treatment with a second chelating agent on the pulverized allogeneic bone and/or cartilage; and (5) grinding the allogeneic bone and/or cartilage after same is treated in step (2), step (3) and optional step (4). Also disclosed are a gel composition, biological scaffolds and a biological gel material containing the bone meal prepared from the above-mentioned method, and a preparation method and use thereof.