| 发明名称 |
MEDICAMENT FOR SUPPRESSING MALIGNANT TUMOR METASTASIS |
| 摘要 |
Provided are a novel medicament for suppressing or preventing the metastasis of a malignant tumor such as carcinoma, a novel treatment or prevention method for suppressing or preventing the metastasis of a malignant tumor, etc. The medicament comprises a non-peptidic angiotensin type 2 receptor agonist as an active ingredient. In the medicament, the non-peptidic angiotensin type 2 receptor agonist may be, for example, a sulfonyl malonamide compound. The medicament may be a medicament for use in combination with an anticancer agent and/or an antitumor agent. |
| 申请公布号 |
US2017014419(A1) |
申请公布日期 |
2017.01.19 |
| 申请号 |
US201515301438 |
申请日期 |
2015.04.03 |
| 申请人 |
NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER ;MITSUBISHI TANABE PHARMA CORPORATION |
发明人 |
KANGAWA Kenji;HOSODA Hiroshi;NOJIRI Takashi |
| 分类号 |
A61K31/5375;A61K31/216;A61K31/197;A61K31/495;A61K31/445;A61K31/4465;A61K31/277;A61K31/4406;A61K31/4402;A61K31/4409;A61K31/4965;A61K31/505;A61K31/415;A61K31/42;A61K31/341;A61K31/381;A61K31/421;A61K31/426;A61K31/47;A61K31/4184;A61K31/404;A61K31/4164;A61K31/423;A61K31/4035;A61K31/517;A61K31/519;A61K31/454;A61K31/496;A61K31/357;A61K31/4192;A61K31/41;A61K45/06;A61K9/00;A61K31/18 |
主分类号 |
A61K31/5375 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for suppressing or preventing one or more of (1) the metastasis of a malignant tumor, (2) the exacerbation and/or augmentation of the metastasis of a malignant tumor caused by an anticancer agent and/or an antitumor agent, or (3) the exacerbation and/or augmentation of the metastasis of a malignant tumor associated with vascular inflammation, said method comprising:
administering an effective amount of a non-peptidic angiotensin type 2 receptor agonist to a subject in need thereof. |
| 地址 |
Suita-shi, Osaka JP |
