发明名称 MARKERS OF ACUTE KIDNEY FAILURE
摘要 The present invention relates to a method of determining the risk of acute kidney injury comprising determining the amount of a marker selected from VCAN, NRP1, CCL2, CCL19, COL3A1, GZMM or any combination thereof in a sample.
申请公布号 US2017016070(A1) 申请公布日期 2017.01.19
申请号 US201615219075 申请日期 2016.07.25
申请人 Oberbauer Rainer 发明人 Oberbauer Rainer;Mayer Bernd;Perco Paul;Kainz Alexander
分类号 C12Q1/68;G01N33/68 主分类号 C12Q1/68
代理机构 代理人
主权项 1. A method for treating a patient in need of treatment with an antibiotic, an anti-inflammatory agent, or a contrast medium, comprising: obtaining a biological sample from the patient; measuring expression level of at least one kidney risk factor (KRF) in the sample, wherein the KRF is selected from the group consisting of VCAN, NRP1, CCL2, CCL19, COL3A1 and GZMM; detecting upregulation of the KRF in the biological sample with respect to one or more control samples obtained from subjects without acute kidney injury disease; and administering an antibiotic other than an aminoglycoside antibiotic, an anti-inflammatory agent other than an NSAID, or a contrast medium other than an iodinated contrast medium to the patient when upregulation of the KRF is detected in the biological sample.
地址 Vienna AT