GENES ENCODING SECRETED PROTEINS WHICH IDENTIFY CLINICALLY SIGNIFICANT PROSTATE CANCER

摘要

The present invention relates to the field of cancer. More specifically, the present invention provides compositions and methods for identification of individuals having clinically significant cancer. In one embodiment, a method for treating a subject having prostate cancer comprises the steps of (a) obtaining a biological sample from the subject; (b) performing an assay on the sample obtained from the subject to measure the levels of one or more protein biomarkers listed in Table 1; (c) comparing the measured levels of one or more protein biomarkers to one or more reference controls to identify the subject as having high grade prostate cancer, low grade prostate cancer or no prostate cancer; and (d) treating the subject with one or more treatment modalities appropriate for a subject having high grade prostate cancer or low grade prostate cancer.

主权项

1. A method for treating a subject having high grade prostate cancer comprising the steps of:
a. obtaining a biological sample from the subject; b. performing an assay on the sample obtained from the subject to measure the levels of one or more protein biomarkers listed in Table 1; c. identifying the subject as having high grade prostate cancer based on a comparison of the measured levels of one or more protein biomarkers to one or more reference controls; and d. treating the subject with one or more treatment modalities appropriate for a subject having high grade prostate cancer.