RECOMBINANT PHAGE AND METHODS OF DETECTING LISTERIA
摘要
Composition and methods for the detection of one or more target microbe(s) are provided. Compositions of the disclosure include at least one recombinant phage capable of infecting a target microbe, said phage comprising at least a capsid protein sequence, a ribosome binding site, and a codon-optimized marker. Compositions of the disclosure may further include an aqueous solution that enhances the ability to detect marker expression upon phage infection of the target microbe. In some embodiments the target microbe is Listeria.
申请公布号
WO2017011309(A1)
申请公布日期
2017.01.19
申请号
WO2016US41529
申请日期
2016.07.08
申请人
SAMPLE6 TECHNOLOGIES, INC.
发明人
KOERIS, Michael Sandor;CAPPILLINO, Michael;KRZYMANSKA-OLEJNIK, Edyta;BROWNELL, Daniel Robert;SHIVERS, Robert Patrick;BOWERS, Jayson L.;LU, Timothy Kuan-Ta