发明名称 |
CLOMIPHENE SYNTHESIS USING A SINGLE SOLVENT |
摘要 |
The present invention provides a one-pot method for synthesizing clomiphene (a mixture of the isomers cis-clomiphene and trans-clomiphene) utilizing a single solvent. In a preferred embodiment, the single solvent is dichloromethane (DCM, also known as methylene chloride). The present invention provides an improved method for synthesizing clomiphene and purifying clomiphene isomers. |
申请公布号 |
EP3116488(A1) |
申请公布日期 |
2017.01.18 |
申请号 |
EP20150761286 |
申请日期 |
2015.03.09 |
申请人 |
Repros Therapeutics Inc. |
发明人 |
PODOLSKI, Joseph, S.;HSU, Kuang |
分类号 |
A61K31/138 |
主分类号 |
A61K31/138 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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