| 发明名称 | Anti-tumor T cell immunity induced by high dose radiation | ||
| 摘要 | Cancer treatment is provided, by irradiating an individual with a localized, high single dose or short course of doses at a primary tumor site; collecting T cells from the individual after a period of time sufficient activation of an anti-tumor response; treating the individual with an effective dose of dose of chemotherapy; and reintroducing the T cell population back to the individual. | ||
| 申请公布号 | US9545444(B2) | 申请公布日期 | 2017.01.17 |
| 申请号 | US201514750769 | 申请日期 | 2015.06.25 |
| 申请人 | The Board of Trustees of the Leland Stanford Junior University | 发明人 | Strober Samuel;Filatenkov Alexander |
| 分类号 | A61N5/00;A61K41/00;A61K45/06;A61K35/12;A61N5/10;A61K35/17;A61K35/28 | 主分类号 | A61N5/00 |
| 代理机构 | Bozicevic, Field & Francis LLP | 代理人 | Sherwood Pamela J.;Bozicevic, Field & Francis LLP |
| 主权项 | 1. A method for generating a population of T cells for treating cancer, the method comprising: subjecting an individual to a high dose of radiation at a tumor site; collecting a population of cells from the individual after a period of time sufficient for activation of T cells, wherein the collected population of cells comprises T cells and CD34+ cells; and purifying the T cells from the collected population of cells. | ||
| 地址 | Stanford CA US | ||