HBED-BISPHOSPHONATES, RADIOMETAL CONJUGATES THEREOF AND THEIR USE AS THERANOSTIC AGENTS

摘要

The present invention relates to compounds according to Formula (I) or Formula (II), which are potential bone imaging agents and therapeutic agents for treating bone tumors and metastases. Certain compounds labeled with 68Ga displayed excellent bone uptake and retention. The present invention also relates to pharmaceutical compositions comprising a pharmaceutical acceptable carrier and a compound of Formula (I) or Formula (II) or a pharmaceutically acceptable salt thereof.