发明名称 |
Humanized and chimeric monoclonal antibodies to CD47 |
摘要 |
Humanized or chimeric anti-CD47 monoclonal antibodies are provided. The antibodies bind to and neutralize human CD47, and find use in various therapeutic methods. Preferred are non-activating antibodies. The invention includes isolated antibodies and derivatives and fragments thereof, pharmaceutical formulations comprising one or more of the humanized or chimeric anti-CD47 monoclonal antibodies; and cell lines that produce these monoclonal antibodies. Also provided are amino acid sequences of the antibodies. |
申请公布号 |
AU2016273893(A1) |
申请公布日期 |
2017.01.12 |
申请号 |
AU20160273893 |
申请日期 |
2016.12.14 |
申请人 |
The Board of Trustees of the Leland Stanford Junior University |
发明人 |
Liu, Jie;Weissman, Irving L.;Majeti, Ravindra |
分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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