COMPOSITIONS AND METHODS FOR DETECTING SNP(S) ASSOCIATED WITH DIABETES

摘要

In one aspect, provided herein are set of primers and use of the same for the detection of SNPs associated with diabetes. In certain embodiments, the primers used to detect SNP sites associated with diabetes comprise Primer Set 1 to Primer Set 47. The experiments show: the genotyping results of the SNP sites associated with diabetes can be accurately detected by the primers disclosed herein, and the risk of individuals can be comprehensively evaluated and the result is more accurate than the single site analysis. In addition, SNPs disclosed herein are verified as associated with type 2 diabetes and its complications, which are especially suitable for the prevention and individualized treatment for type 2 diabetes in East Asian, for example, in China.

主权项

1. An isolated polynucleotide comprising a nucleic acid sequence having at least about 85%, at least about 90%, at least about 95%, at least about 99%, or 100% sequence homology or identity with any of SEQ ID NOs: 1-141.