发明名称 |
ENGINEERED TISSUE CONSTRUCTS |
摘要 |
A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate. |
申请公布号 |
EP3114212(A2) |
申请公布日期 |
2017.01.11 |
申请号 |
EP20150758207 |
申请日期 |
2015.03.09 |
申请人 |
Case Western Reserve University;Worcester Polytechnic Institute |
发明人 |
ALSBERG, Eben;DIKINA, Anna D.;ROLLE, Marsha W. |
分类号 |
C12N5/00;A61F2/20;C12N5/02 |
主分类号 |
C12N5/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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