Medical device

摘要

The present invention relates to a medical device, particularly a vascular graft or an arteriovenous (AV) graft for haemodialysis. The medical device comprises a layer of porous silk fibroin matrix and a layer of knitted silk fibers. The invention further relates to processes of manufacture of such medical devices and methods of use of such devices.

主权项

1. A medical device comprising a tubular body and a long axis, wherein the tubular body comprises:
(a) at least one layer of porous silk fibroin matrix; and (b) at least one layer of knitted silk fibres,wherein the luminal layer is a layer of porous silk fibroin matrix,and wherein one or more of the layers of knitted silk fibres is present, partially or completely, in an annulate, helical, threaded, spiral, grooved, corrugated or crimped form or profile.