| 发明名称 | Methods and compositions for modulating G-alpha-Q signaling | ||
| 摘要 | The present invention provides compositions and methods for modulating G-alpha-q activity and methods of screening of test substances for the ability to modulate G-alpha-q activity. | ||
| 申请公布号 | US9540620(B2) | 申请公布日期 | 2017.01.10 |
| 申请号 | US201314398678 | 申请日期 | 2013.03.08 |
| 申请人 | The University of North Carolina at Chapel Hill | 发明人 | Sondek John;Harden Thomas Kendall;Waldo Gary Lynn;Barrett Matthew Owen;Charpentier Thomas Henry |
| 分类号 | A61K38/00;C12N9/16;A61K38/46;C07K14/47;A61K47/48;C12Q1/34 | 主分类号 | A61K38/00 |
| 代理机构 | Myers Bigel, P.A. | 代理人 | Myers Bigel, P.A. |
| 主权项 | 1. A method of downregulating G-alpha-Q signaling in a cell, comprising introducing into the cell a peptide comprising the amino acid sequence HQDYAEALANPIKHVSL-Nle-DQR (SEQ ID NO:1). | ||
| 地址 | Chapel Hill NC US | ||