| 摘要 |
The present invention is directed to substituted triazolo bicycliccompounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis, Parkinson's disease, Parkinson's disease dementia (PDD), or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction. |
| 申请人 |
MERCK SHARP & DOHME CORP.;MORRIELLO, Gregori J.;CHANG, Lehua;FOSTER, Ashley;CHEN, Yili;DWYER, Michael;GUO, Zack Zhiqiang;WANG, Ming;XU, Shimin;BO, Yingjian;FU, Jianmin |
发明人 |
MORRIELLO, Gregori J.;CHANG, Lehua;FOSTER, Ashley;CHEN, Yili;DWYER, Michael;GUO, Zack Zhiqiang;WANG, Ming;XU, Shimin;BO, Yingjian;FU, Jianmin |
