发明名称 |
METHOD FOR PRODUCING 4-BORONO-L-PHENYLALANINE HAVING 18F ATOM INTRODUCED THEREINTO, AND PRECURSOR OF 4-BORONO-L-PHENYLALANINE HAVING 18F ATOM INTRODUCED THEREINTO |
摘要 |
The purpose of the present invention is to provide: a novel method for producing 18 F-labeled 4-boronophenylalanine (BPA) ; and a precursor of 18 F-labeled BPA. 18 F-labeled BPA can be produced by preparing a compound represented by formula (1) and using the compound. In the formula, R1 represents a bromo group, an iodo group, a fluoro group, a diazaborinane derivative, BX3- or BX3-M+ (wherein X represents a halogen atom; and M+ represents a monovalent monoatomic cation, a polyatomic cation or a complex cation). |
申请公布号 |
EP3112340(A1) |
申请公布日期 |
2017.01.04 |
申请号 |
EP20150754420 |
申请日期 |
2015.01.28 |
申请人 |
Stella Pharma Corporation;Osaka Prefecture University Public Corporation |
发明人 |
TAKENAKA, Hiroshi;OHTA, Yoichiro;TAGUCHI, Yusuke;UEDA, Sayuri;ISHINO, Yuko;YOSHIKAWA, Tomohiro;NAKASHIMA, Hideki;UEHARA, Kohki;KIRIHATA, Mitsunori |
分类号 |
C07C47/55;C07B59/00;C07C45/63;C07F5/02 |
主分类号 |
C07C47/55 |
代理机构 |
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代理人 |
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地址 |
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